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There are many types of medicinal treatments used to help with weight loss, and one of the most well-known types are GLP-1 agonists. These drugs behave like natural molecules in your body to help you lose weight for good. Our experts break down what GLP-1 agonists are, what they do, and how they can be used as a weight management treatment.
GLP-1 stands for glucagon-like peptide-1, and despite its complex name, its function can be summarised into a simple yet crucial task: regulating blood sugar. It's part of the incretin system, a group of metabolic hormones you produce naturally in your gut that influence the amount of insulin released after eating.
Insulin is a hormone that allows cells to take in glucose from the bloodstream. When you eat, your body breaks down carbohydrates into glucose, causing a rise in blood sugar levels. When food enters your digestive tract, GLP-1 sends a signal to your pancreas, triggering it to release insulin. This helps your cells absorb and use glucose for energy, bringing your blood sugar levels back to a normal level.
GLP-1 is more than just a messenger for insulin release. It also slows down the rate your stomach empties, which reduces the post-meal surge in blood sugar levels and helps you feel full quicker.
Scientists have developed a synthetic version of GLP-1s called GLP-1 agonists. These drugs mimic the action of natural GLP-1, helping to manage blood sugar levels and make you feel full when you’ve eaten. They’re often used to regulate blood sugar if you have diabetes, but they’re also effective as a medical weight loss treatment. Examples of GLP-1 agonists are dulaglutide (Trulicity) and semaglutide (Ozempic).
Injectable weight loss medications like GLP-1 agonists are effective for many people, but results come from a combination of treatment and lifestyle changes. They can be used to boost and support your weight loss alongside a healthy diet and regular exercise.
Learn more about non-surgical weight loss solutions at Levity.